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What is the difference between coronary artery disease and peripheral vascular disease? PAD is similar to coronary artery disease (CAD) Peripheral artery disease is a narrowing of the peripheral arteries serving the legs, stomach, arms and head. (" Peripheral " in this case means away from the heart, in the outer regions of the body.) Both PAD and coronary artery disease (CAD) are caused by atherosclerosis.
How does exercise help peripheral artery disease? Untreated, PAD can lead to chronic pain (claudication), chronic infections and in the most severe cases, amputation of the limbs. Research has shown that exercise can be highly effective in increasing leg circulation and reducing the pain that accompanies activity (called claudication).